Structural Biology & Biophysics Program @ Duke University

SBB Seminar Series

All seminars are regularly held every Monday in Room 437 of the Nanaline Duke Building, at 4:15 unless otherwise indicated.

(Duke class times push SBB seminar to be after 3:20-4:10 class)

Non-SBB students and faculty are, of course, welcome to attend. Attendance is required for SBB Program students.
Food and beverages (typically, pizza and sodas) will be served at each seminar.

Everyone is expected and encouraged to ask questions.!

Current Seminar schedule maintained as a Google Calendar: 2015-2016 SBB Google Calendar

Seminars FALL 2014, SPRING 2015, and some earlier, listed below in this web page

FALL 2014: Date
Speaker
September 22 2014
Dong Wang
UCSD, Pharmacy & Pharmaceutical Sciences
Molecular Basis of RNA Pol II Transcription and DNA Lesion Recognition
October 6 2014
(CANCELLED)
GO TO CBB SEMINAR 11:30 FRENCH 4233
JOHN CHODERA "Redesigning Drug Design"
October 13 2014
NO SBB SEMINAR
BASIC SCIENCE DAY
October 20 2014
Brittany Morgan
Hargrove/Chemistry
Development of Multivalent Inhibitors to Disrupt Long Non-coding RNA-Protein Interactions
October 27 2014
Kyle Daniels
Oas/Biochem
Mechanistic affinity determination: Using kinetics to determine the binding affinities of conformational states in RNase P Protein
November 24 2014
Yang Qi
Oas/Biochem
The Structure of a Flexible Two Domain Protein: Fitting Residual Dipolar Coupling Data to a Continuous Orientation Distribution Model
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SPRING 2015: Date
Speaker
January 19 2015
MLK day
NO SBB seminar
January 26 2015
Swati Jain
Richardson/Biochem
Analysis, validation and correction of RNA 3D structures
February 2 2015
Christopher Williams
Richardson/Biochem
A Twisted Tale of Peptide Dihedrals
February 9 2015
(Biophysics Society Mtg week)
NO SEMINAR

February 16 2015
Bradley Hintze
Richardson/Biochem
The rotamer and its bond angles
March 9 2015
(Duke Spring Break)
NO SEMINAR

March 23 2015
Mark Hallen
Donald/Biochem
COMETS: Constrained Optimization of Multistate Energies by Tree Search
March 30 2015
Keri Hamilton
Brennan/Biochem
Elucidating the Mechanism of PrfA-Mediated Virulence in Listeria monocytogenes
April 6 2015
Richard Wolfenden & Charlie Carter
UNC Dept. Biochemistry & Biophysics
"The Temperature Dependence of Amino Acid Hydrophobicities"
"tRNA Acceptor-Stem and Anticodon Bases Form Independent Codes Related to Protein Folding"
April 13 2015
Laura Ganser
Al-Hashimi/Biochem
Targeting HIV-1 TAR with Small Molecules
April 20 2015
Cancelled

April 27 2015
Alex Kovach
Brennan/Biochem
The Many Lives of Hfq
May 4 2015
NO SEMINAR

May 11 2015
Doug Barrick
Biophysics Dept., Johns Hopkins Univ.
Using linear symmetric proteins to quantify cooperativity in folding
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=====================ARCHIVE==2013-2014=============
FALL 2013: Date
Speaker
September 9 2013
Brent Hoffman
Biomedical Engineering
Visualizing Molecular Forces Across Specific Proteins in Living Cells
September 16 2013
Amanda Hargrove
Chemistry
Developing small molecules to target nucleic acids in human disease
September 23 2013
Bonnie Cuthbert
Brennan,Schumacher/Biochemistry
Regulation of Francisella pathogenicity: structural and biochemical studies
September 30 2013
Jorg Grandl
Neurobiology
The mechanism of activation of TRP ion channels by hot or cold temperatures
October 7 2013
Marsha Hirschi
Lee/Biochemistry
Structural Biology of Equilibrative Nucleoside Transporters
October 14 2013
NO SBB SEMINAR
BASIC SCIENCE DAY
October 21 2013
Steven Lewis
Richardson/Biochemistry
Computational protein-protein interface redesign for bispecific antibodies
October 28 2013
Swati Jain
Richardson/CBB
Using ERRASER to rebuild RNA structures and finding new backbone conformers
November 4 2013
Gary Kapral
Richardson/Biochemistry
The OHO pentaloop: uncovering a new RNA backbone motif
November 11 2013
Daina Zeng
Agile Sciences, RTP
Fundamentals of Job Searching in Industry
November 18 2013
Jungki Min
Brennan/Biochemistry
Structural and biochemical studies on HipB-hipBA operator complexes
November 25 2013
Christopher Williams
Richardson/Biochemistry
Journeys beyond alpha helix: The world of non-repeating secondary structure
December 2 2013
Jo Anna Capp
Oas/Biochemistry
Describing the statistical conformation of highly flexible proteins
December 9 2013
Bradley Hintze
Richardson/Biochemistry
Complex Correlations in Conformational Space
December 16 2013
Zack Scholl
Marszalek,Yang/CBB
Unraveling Luciferase - understanding the energy landscape of a large multidomain protein
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SPRING 2014: Date
Speaker
January 6 2014
R. J. Perz-Edwards
Cell Biology
Catching muscle in flagrante delicto by real-time X-ray diffraction movies and stop-action cryo-trapped electron microscopy
January 13 2014
Keri Hamilton
Brennan/Biochem
Structural and biochemical characterization of a MerR-like regulator from Neisseria gonorrhoeae and Streptococcus pneumoniae
January 20 2014
NO SBB SEMINAR
MLK Day
January 27 2014
Porsha Shaw
Schumacher/Biochem
Structural and Biochemical Studies on Trypanosoma brucei protein, 1590
February 3 2014
Lindsay Deis
Oas/Biochem
Conformational heterogeneity of staphyloccocal protein A
February 10 2014
Joe Bellucci
Chilkoti/BME
Recombinant protein purification and site-specific modification using the Sortase A transpeptidase
February 17 2014
Yang Qi
Oas/Biochem
Characterizing inter-domain motions of Staphylococcal protein A using a continuous model
February 24 2014
Dave Thirumalai
Univ. Maryland
Theory of stepping and stomping of Myosin V
March 3 2014


March 10 2014
Brian Watts
Toone/Chem
Investigations into the Thermodynamics of Multivalent Ligand Binding
March 17 2014
Nick Warischalk
Kiehart/Biochem
Changes to the lever arm of drosophila non-muscle myosin II
March 24 2014
Jin Liang
Stamer/BME
Mechanical stretch induced endothelial-mesenchymal transition of Trabecular Meshwork cells
March 31 2014
Alex Kovach
Brennan/Biochem
Characterization of Listeria monocytogenes Hfq highlights diversity between species
April 7 2014
Minjung Choi
Lefkowitz/Biochem
Stable complex formation of Beta2-adrenergic receptor and beta-arrestin1 by disulfide crosslinking
April 14 2014
NO SBB SEMINAR
attend the Biochemistry Spring Symposium
April 21 2014
Yi Miao
Brennan/Biochem
Targeting Trehalose Biosynthesis Pathway in Pathogenic Fungi
April 28 2014
Mark Hallen
Donald/Biochem
Energy as polynomials in internal coordinates (EPIC): A compact representation of continuous energy surfaces for more efficient protein design
May 5 2014
Jessica Wojtaszek
Zhou/Biochem
May 12 2014
Kyle Daniels
Oas/Biochem
May 19 2014
Roy Hughes
Oas/Biochem
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=====================ARCHIVE======2012--2013=========
SPRING 2013: Date
Speaker
January 14 2013
Christopher Williams
Richardson/Biochemistry
January 21 2013
MLK day
NO SEMINAR
January 28 2013
Lei Mao
First-Year SBB
Rational Drug Design Targeting Nuclear Transport Machinery
February 4 2013
NO SEMINAR

February 11 2013
NO SEMINAR

February 18 2013
Porsha Shaw
Schumacher/Biochemistry
Structural and Biochemical Studies on NASP Family of Histone Chaperones
(February 21-23) 2013
SBB recruiting weekend

February 25 2013
Brian Watts
Toone/Chemistry
Investigations into the Thermodynamics of Multivalent Ligand Binding
March 4 2013
Bradley Hintze
Richardson/Biochemistry
Finding Real Rotamers Using Real-space Correlation Coefficients
March 11 2013
SPRING BREAK

March 18 2013
Jeehyun Lee
Schumacher/Biochemistry
The Molecular Mechanism of the Archaeal pNOB8 Motor Protein ParA
March 25 2013
Yang Qi
Oas/Biochemistry
NMR Dynamic Studies of a Multi-domain Protein SpA-N
April 1 2013
Roy Hughes
Oas/Biochemistry
Modeling the Unfolded State
April 8 2013
Nicholas Polizzi
Beratan-Therien/Chemistry
April 15 2013
Marsha Hirschi
Lee/Biochemistry
April 22 2013
Jack Hsu
Nicchitta/Cell Biology
Identification and Characterization of mRNA Anchors on the Endoplasmic Reticulum
April 29 2013
Diana Fusco
Charbonneau/CBB
Can patchy spherical cows help understand protein crystallization?
May 6 2013
Matt Redinbo
Chemistry, UNC
Dynamics of Human-Microbiota Symbiosis
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FALL 2012: Date
Speaker
August 27 2012

NO SBB SEMINAR
September 3 2012
LABOR DAY
NO SBB SEMINAR
September 10 2012
Stefan Zauscher, Brian Mann, Piotr Marszalek, and Terry Oas

Using Atomic Force Spectroscopy and the theory of Stochastic Resonance to study protein folding and lipid bilayers.
September 17 2012
Bruce Donald
11:30 AM, 4233 French Building
Protein Interface Design, Cystic Fibrosis and HIV
September 24 2012
Pamela Bjorkman, Caltech
SAC Lecture: 4pm-5pm Albert Eye Research Institute Auditorium
(1st floor in annex to Eye Ctr Bldg, between Carl Bldg and Duke North)
Engineering Immunity against HIV
October 1 2012

NO SBB SEMINAR
October 8 2012
Keri Hamilton
Brennan/Biochemistry
Characterization of three gonococcal ROS-mediated transcriptional regulators
October 15 2012
FALL BREAK
NO SBB SEMINAR
October 22 2012
Yinan Wei
Chemistry Dept, Univ of Kentucky
Assembly of protein oligomers in the cell membrane
October 29 2012
Carleen Morris
Toone/Chemistry
Developing Hybrid Material Interfaces for Microcontact Printing and Molecular Recognition
November 5 2012
CANCELLED

November 12 2012
Jonathan Li
Oas/Biochemistry
Structural Characterization of Lambda Repressor N-Terminal Domain Unfolded State
November 19 2012
Lindsay Deis
Richardson/Biochemistry
Getting Better Information Into - and Out of - High-Resolution Structures
November 26 2012
Zack Scholl
Yang and Marszalek/CBB
Developments in probing cotranslational protein folding with AFM and SMD
December 3 2012
Jo Anna Capp
Oas/Biochemistry
Exploring the conformational flexibility of SpA-N by Small-Angle X-ray Scattering
December 10 2012
Mark Hallen
Donald/Biochemistry
Protein design with more realistic continuous flexibility
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Spring 2012: Date
Speaker
January 9th 2012
Christopher Williams
Richardson/Bochemistry
Finding the Cool Stuff: Alpha Carbons, Hydrogen Bonds, and Automated Motif Identification in Proteins
January 16th 2012
NO SEMINAR
MLK day
January 23rd 2012
Jungki Min
Brennan/Biochemistry
Stress Response Mechanisms in Pathogens: Multidrug Tolerance (MDT) and Pleiotropic Drug Resistance (PDR)
January 30th 2012
Roy Hughes
Oas/Biochemistry
Modeling the Unfolded State
February 6th 2012
Desmond Moore
Erickson/Cell Biology&Biochemistry
Steps Toward Understanding Cytokinesis in Escherichia coli
February 13th 2012
Keri Hamilton
Brennan/Biochemistry
Structural and biochemical studies on the redox responsive gonorrheal protein NmlR
February 20th 2012
Ali Masoudi
Raetz/Biochemistry
Molecular Determinants of Interactions Between Acyl Carrier Protein and Acyltransferases of Lipid A Biosynthesis
February 27th 2012
Gary Kapral
Richardson/Biochemistry
Contributions of RNA backbone conformers to binding specificity in large RNA-protein complexes
March 4th 2012
NO SEMINAR
Spring Break
March 12th 2012
Beth McSweeney
Beese/Biochemistry
Structure of human exonuclease 1 DNA complexes suggest a unified mechanism for nuclease family
March 19th 2012
Jeehyun Lee
Schumacher/Biochemistry
Probing the molecular mechanism of archaeal DNA segregation
March 26th 2012
Porsha Shaw
Schumacher/Biochemistry
Characterization of N1 Family of Histone Chaperones
April 2nd 2012
Yang Qi
Oas/Biochemistry
Dynamic and Structural Characterization of A Multi-domain Protein: SpA-N
April 9th 2012
Hadley Iliff
Schumacher/Biochemistry
Biochemical and Structural Characterization of TbRGG2: A kRNA Accessory Factor
April 16th 2012
Jonathan Li
Oas/Biochemistry
Probing the Conformational Ensemble of an Isolated Helical Peptide from lambda Repressor
April 23rd 2012
Yi Miao
Brennan/Biochemistry
Trehalose synthesis pathway in Cryptococcus gattii
April 30th 2012
Yves Wang
Toone,Beratan/Chemistry
How can we experimentally 'simulate' ligand binding?
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