Structural Biology & Biophysics Program @ Duke University


The curriculum

Summary

The Director of Graduate Studies and an Advisory Committee advise new students on laboratory rotations and a course of study. In the first semester in graduate school, students take courses, some full semester, some chosen from half-semester courses designed to give all students a basic knowledge of fundamental principles and techniques. The advising committee may require or recommend courses depending on the student's background, interests, and with a view of course requirements of the Department(s) the particular student is likely to join.

Training

First year: Course work: the usual SBB courses and others chosen for the individual student's interests and needs. Attendance at SBB seminars, rotations in 3 different laboratories. Toward the end of the second semester, the student chooses and the advisory committee approves a thesis advisor and topic.

All later years: emphasis is on research, possibly some course work, attendance at SBB seminars.

Third year (Fall): preliminary examination (to actually qualify as a candidate for the PhD degree).

Completion: Thesis acceptance, public seminar, thesis examination.

Courses: specific SBB courses usually taken by all SBB students, (also see department listings in the areas of your interests)

222. (Spr) Structure of Biological Macromolecules. J. & D. Richardson.

258-259. (Fall, half-courses) Structural Biochemistry I & II. Prerequisite: biochemistry, organic chemistry and physical chemistry or consent of instructor. L. Beese, H. Hellinga and staff.

291. (Spr) Physical Biochemistry I: Prerequisite: undergraduate physical chemistry and one year of calculus or consent of instructor. T. Oas and staff .

292. (arranged as a tutorial) Physical Biochemistry II: Transient kinetics, computational methods, multidimensional NMR, x-ray crystallography, thermodynamics of association. Prerequisite: Structural Biology and Biophysics or consent of instructor. T. Oas and staff.

345 (Fall), 346 (Spr). Structural Biology and Biophysics Seminar. Required of all SBB students.

High resolution crystal structures reveal a common but subtle mode of local backbone motion -- the "backrub".

SBB student Ian Davis, Richardson lab
Structure. 2006 Feb;14(2):265-74